Organ mimics are helping decode complex diseases On the lab bench, inside a Petri dish nestled between two metal coils, sits an unassuming glob of jelly. But this is no ordinary jelly – it is a squishy gel filled with magnetic particles and cells from the human lung. Once the power switches on, magnetic […]
Category: Longform
Dark Side of the Genome
There’s more than meets the eye when it comes to ‘junk’ DNA In September 2012, as the final papers from the ENCODE (ENCyclopedia Of DNA Elements) project rolled out, the mood among many molecular biologists was triumphant. After more than a decade of coordinated experiments across dozens of laboratories, the consortium made a bold […]
Transforming Mobility
Designing an electric future A quiet hum is redefining mobility. More than a century ago, the rhythm of modern travel was measured by hoofbeats – the rhythmic sound of iron shoes on cobbled streets. Then came the gas-chugging Internal Combustion (IC) engines, whose roars marked a revolution of speed and power. Now, mankind stands […]
The Perceptron
Tracing the history of the earliest neural network The year was 1958 when the United States Navy unveiled what they called a thinking machine – a perceptron. It was an IBM 704 equipped to “react” to and learn from its inputs. The giant computer simulator was the brainchild of Frank Rosenblatt, a scientist […]
Becoming Glass
The alluring mystery of an amorphous solid Glass is everywhere. You scroll over it on your phone, you drink from it, it’s in the spectacles perched on your nose and in the windows of your house. But how does it form? To picture that, imagine molten glass. As a liquid, it can flow; its […]
City Slickers
Why urban diseases like rabies and dengue are so hard to control Less than a kilometre from Bengaluru’s Lalbagh botanical garden lies the Bisilu Maramma Devi temple. The goddess has another name: Plague Maramma. Devotees believe that the deity harnesses the sun’s power to kill bacteria and viruses and ward off illnesses. The temple […]
In the ‘AI’ of the beholder
Beauty and bias in perceiving art “I feel like we are nearing the end of times. We humans are losing faith in ourselves.” Hayao Miyazaki, the Japanese animator and co-founder of the renowned production house Studio Ghibli, uttered these words in 2016 after seeing an AI-generated animation film for the first time. Nine years […]
The Beauty of Maths
Why some enjoy the subject for what it is Let us begin with an unusual counting puzzle. Imagine two blocks labelled 1 and 2, next to each other on the ground beside a wall. Assume that the ground is frictionless, and that the blocks will not lose energy when they hit each other or […]
The Cosmological Principle
Can it help us understand the unknown universe? One day in the spring of 1543, a canon named Nicolaus Copernicus, lying on his sickbed, suddenly awoke from a coma that he had been put under because of a brain stroke. Resting beside him was the first copy of his magnum opus: De revolutionibus orbium […]
Origin Story
How did life emerge on Earth? (Spoiler alert: We still don’t know) On a cold winter evening in 1952, in a dimly lit lab at the University of Chicago, Stanley Miller, a 22-year-old graduate student, stared at the murky brown sludge in the shake flask in front of him, his stomach sinking. Days of […]