Organ mimics are helping decode complex diseases On the lab bench, inside a Petri dish nestled between two metal coils, sits an unassuming glob of jelly. But this is no ordinary jelly – it is a squishy gel filled with magnetic particles and cells from the human lung. Once the power switches on, magnetic […]
Category: In the lab
Fungal Hues
Demystifying nature’s oldest pigment producers In Shantanu Shukla’s lab, dissecting insects is routine. The well-lit room, located in the Department of Developmental Biology and Genetics (DBG), IISc, is filled with young scientists studying scale insects – tiny plant vampires that feed on the plant phloem sap. The team investigates the intimate relationship between insects […]
The DIY Scientist
Creating under constraint When Umesh Varshney joined IISc as an Assistant Professor, he was excited to dive straight into microbiology research. It was 1991, and he had just returned from his postdoctoral stint at MIT in Cambridge. He planned to study protein synthesis in Escherichia coli and DNA repair in mycobacteria, among other exciting […]
Mission Spin-possible
How electron spins can boost computing You wake up late. Your assignment is due in two minutes. You grab your laptop with a standard 8 or 16 GB RAM, a 512 solid state drive (SSD) that is “supposed” to be fast, a decent processor that usually gets the job done. You press the power […]
Journey of an Experiment
On research, failure and learning to work with the mess The experiment, at least on paper, was simple: watch what happens to the physical forces between cells as a healthy tissue starts becoming cancerous. Push, pull, tension mapped onto something as messy as a living tissue. I remember feeling all tingly when I came […]
Transforming Mobility
Designing an electric future A quiet hum is redefining mobility. More than a century ago, the rhythm of modern travel was measured by hoofbeats – the rhythmic sound of iron shoes on cobbled streets. Then came the gas-chugging Internal Combustion (IC) engines, whose roars marked a revolution of speed and power. Now, mankind stands […]
The Rebel Cell
Scientists are racing to outsmart cancer Mohit Kumar Jolly was reading The Emperor of All Maladies: A Biography of Cancer, a popular science book by Siddhartha Mukherjee, when he became impressed by the idea of fighting against cancer. His interest grew exponentially after he started seeing cancer patients every day at the MD Anderson […]
Becoming Glass
The alluring mystery of an amorphous solid Glass is everywhere. You scroll over it on your phone, you drink from it, it’s in the spectacles perched on your nose and in the windows of your house. But how does it form? To picture that, imagine molten glass. As a liquid, it can flow; its […]
Behind the Biosafety Doors
Staff who support high-stakes research A long walk downhill on Silver Oak Marg leads you to the quiet edge of campus, where the bustle of the main roads fades into the murmur of trees. The air feels cooler here. Just past the Combustion Gasification and Propulsion Laboratory (CGPL), there is a gate on the left. […]
Microbe Slayers
Hunting strategies of predatory bacteria In 1900, a young medical student named Alexander Fleming was studying at St Mary’s Hospital Medical School in London. Fleming also served in the London Scottish Regiment of the Territorial Army, where he became an expert marksman. His talent for shooting caught the eye of the captain of St […]