Redesigning the Genome

An annual synthetic biology competition has spurred UG students to develop novel solutions   In the early 1960s, French scientists Francois Jacob and Jacques Monod figured out how gene expression in bacterial cells is regulated. Since then, scientists began dreaming of manipulating these regulatory circuits in the bacterial genome (the entire set of its genetic […]

Neurolathyrism: An Unsolved Mystery

Experiments in PS Sarma‚Äôs lab at the Department of Biochemistry in the 1960s explored a mystery disease caused by excess consumption of seeds of a controversial pulse crop   For many years, the Department of Biochemistry at IISc worked extensively on nutrition. Its researchers have analysed the importance of vitamin B1 in our diet. They […]